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The only route left was skin
Each added receptor opens a new metabolic lane GIP enhances insulin sensitivity and fat-oxidation signaling, and glucagon increases hepatic energy expenditure
For systemic issues, such as overall gut inflammation, cognitive research, or generalized recovery, intranasal administration is a completely viable route
When that was done, the results started coming
doi: 10.1016/j.phymed.2023.154775 177 LiNZhaoTCaoYZhangHPengLWangYet al
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