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As shown in Figure 3A, reduced expression levels of IL-6 and 8 and MMP3, 12 and 13 were observed in the FOXO4-DRI treated group, which however were concomitantly accompanied with reduced expression of SOX9 and COL2 , as well as increased expression of CDKN2A, CDKN1A , and TP53 (encoding p53)

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Glutathione is a naturally occurring antioxidant in your body, but as you age, production levels decline

A study in lupus-induced mice demonstrated that the NAC prevents glutathione reduction, decreases autoantibody production, and increases nephritis frequency, leading to improved survival rates [11]

(Beijing, China) for editing the manuscript