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stop at least 2 months before conception Ibuprofen caution / NSAIDs increase GI bleeding risk and may blunt renal function alongside GLP-1 drugs Wegovy FDA label / approved for BMI 30, or 27 with at least one weight-related comorbidity SELECT trial / semaglutide 2.4 mg cut major cardiovascular events by 20% over 3.3 years in adults with obesity Does Caffeine Interfere With GLP-1 Medications
Insulin and insulin secretagogues - Adding tirzepatide to insulin or insulin secretagogues (e.g., sulfonylureas, meglitinides) increases the risk of hypoglycemia
Histological Endpoints Liver biopsy remains the reference standard in clinical trials, enabling assessment of steatohepatitis resolution and fibrosis stage
Eventuell ist es sinnvoll, begleitende Parameter zu erheben
Nat Rev Endocrinol (2010) 6(12):68997
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