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doi: 10.1136/jim-2021-001952
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
This is higher than standard recommendations (0.8g/kg) because protein needs significantly increase during caloric restriction to prevent muscle breakdown and support muscle protein synthesis
Overall, GLP-1 RA use did not increase the risk of pancreatitis, and the rate of pancreatitis was similar in patients on a GLP-1 RA versus those who were not (2.5% vs 2.6%
When our levels are low, we might feel less energetic, notice a duller complexion, or find it harder to bounce back from daily physical stress
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