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Despite the encouraging results of GLP-1/glucagon co-agonism in experimental models, different GLP-1 and glucagon co-agonists have shown various levels of efficacy and tolerability in people with obesity and/or T2D, in early phase clinical trials, which may be explained by the different ratio of GLP-1 to glucagon activity between the different molecules [65]
Studies examine the optimal timing, ratios, and dosing strategies for maximum synergy
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As seen in Algorithm 1, the LSTM algorithm for skin cancer detection can autonomously and flexibly acquire spatial hierarchies of characteristics, making it suitable for skin image processing and assessment
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