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Real-world outcomes from thousands of patients show that those who titrate gradually from 2.5 mg upward, supported by genetic insights and behavioral coaching, achieve sustained weight loss of 1525% over six months

The bigger outcome is that this study needs to be conducted on a larger scale

Another practical observation is that many people regain weight once the medication is stopped, suggesting the underlying metabolic drivers may not have been fully addressed

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Protein intake and resistance training remain the better-supported tools for lean-mass support