TB-500 is a synthetic fragment of Thymosin Beta-4 whose core proposed action is the sequestering of G-actin to regulate actin polymerization the process behind cell migration in wound healing and which has been linked preclinically to angiogenesis and reduced inflammation [3] [4]
This week, the FDA's Pharmacy Compounding Advisory Committee is expected to recommend whether seven peptides can move to the Section 503A Bulk Drug Substances List, a recommendation that could have significant implications for patient access, personalized care, and the future of compounding
However, experts in the area generally concur that a combination of data from multiple endpoints is needed to discriminate sensitizing and/or irritant substances in vitro
Additionally, epidemiological studies suggest that acetaminophen use may significantly increase the risk of asthma, allergies, and eczema in children
Ongoing trials are comparing outcomes