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Early laboratory work has examined its ability to influence synaptic connections and support neuronal signaling, but these findings come primarily from animal studies and in-vitro models, not from human clinical trials

furthermore, low-dose intravaginal estrogens are the gold standard for treating genitourinary syndrome of menopause that cannot be sufficiently treated with non-hormonal therapies

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11, 23 We could not find GLP1R in any of the human papillary thyroid carcinomas, neither by immunohistochemistry nor by autoradiography, again as opposed to Gier et al , 22 who found immunoreactivity attributed to GLP1R in 18% of the cases, but based on an insufficiently validated immunohistochemical protocol