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In summary, although current studies suggest that ferroptosis plays a central regulatory role in the pathological sequence of PVLlinking hypoxiaischemia, inflammatory infiltration, and white-matter necrosisand provides a new mechanistic basis for understanding the pathway from periventricular iron accumulation to oligodendrocyte loss and motor developmental impairment, several essential gaps remain
Wang J, Pan Y, Hu J, Ma Q, Xu Y, Zhang Y
Vilstrup H, Amodio P, Bajaj J, et al
This reaction protects the cellular machinery and reduces ROS-induced cellular damage
10.2337/dc11-1108 2 AbdelkaderN
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