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64 RosenwasserS.Graff van CreveldS.SchatzD.MalitskyS.TzfadiaO.AharoniA.et al (2014)
Figure 8 4.6.1 Iron metabolism dysregulation in the blood and CSF of ALS patients Multiple studies and meta-analyses have demonstrated elevated serum ferritin levels in ALS patients compared to healthy controls (334336, 340)
Dopaminergic neurons are especially prone to ferroptotic damage, partly because dopamine metabolism itself can generate reactive quinone species, contributing to oxidative stress
Similar to Parkinsons and liver disease, researchers are hopeful of the role of glutathione in reducing this oxidative stress and protecting the blood vessels
Nutrition journal , 15 , 1-7
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