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Potential benefits: Lower glucose exposure, less insulin required, sometimes improved variability
Kamel Hassan is a family medicine specialist and aesthetic medicine expert practicing in the United Arab Emirates
[1] [2] Available under brand names including Ozempic, Wegovy, and Rybelsus, this medication mimics the action of naturally occurring GLP-1, a hormone that plays multiple roles in glucose metabolism and appetite regulation
In the year following discontinuation of semaglutide or liraglutide, patients with class 3 obesitya BMI of 40 or greaterwhen starting a GLP-1 medication were much more likely to maintain or lose additional weight compared to those who started treatment with a healthy weighta BMI between 18.5 and 25
A 2025 narrative review published in Frontiers in Clinical Diabetes and Healthcare analyzed the existing body of research on GLP-1 receptor agonists and exercise
