As can be observed in Table 1 , basal insulin was reduced by ~10-25% and bolus doses by ~15-33% in RCTs
Both are licensed for weight management in the UK, but Wegovy generally produces more substantial weight reduction and may be preferred due to its convenient weekly dosing schedule
Therefore, AD is also called type 3 diabetes (12, 13)
Some specialists also expect future study in women with polycystic ovary syndrome, sometimes called PCOS or PMOS, since weight management is often part of care there, though retatrutide has not yet been tested specifically for this condition
Among the cardiovascular disease events, 30 participants experienced myocardial infarction, 21 cases of stroke, and six cases of heart failure