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Recent genomic and transcriptomic profiling of tumors of patients with GBM following treatment with PD-1 inhibitors nivolumab or pembrolizumab revealed a significant enrichment of PTEN mutations associated with immunosuppressive expression signatures in non-responders [107]
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10.1016/j.ejmech.2018.01.011 113 YamadaN.KarasawaT.KimuraH.WatanabeS.KomadaT.KamataR.et al (2020)
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