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Roles of the glutathione- and thioredoxin-dependent reduction system in the Escherichia coli and Saccharomyces cerevisiae responses to oxidative stress

Helps achieve a uniform complexion

The key reaction catalyzed by GSTs is the conjugation of electrophilic xenobiotics with the endogenous tripeptide GSH

doi: 10.3389/fphar.2026.1761748 Received 05 December 2025 Revised 25 March 2026 Accepted 01 April 2026 Published 22 April 2026 Volume 17 - 2026 Edited by Ming Xu, Shimonoseki City University, Japan Reviewed by Gaetano De Siena, University of Florence, Italy Wei Guo, University of North Carolina at Greensboro, United States Updates Copyright 2026 Nandagopal and Manickam

Although this general redox cycling concept (Fig