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Bacteroides thetaiotaomicron and Lactobacillus johnsonii generate fatty acids, particularly oleic acid and palmitic acid, regulate inflammatory immune responses, and eliminate Candida glabrata in the DSS-induced colitis mouse model ( Current antifungal drugs Currently, the first-line clinical antifungal drugs include polyenes (e.g., amphotericin B), azoles (e.g., fluconazole) and echinocandins (e.g., caspofungin) (Wiederhold, 2017

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Considering the protective effect of CAT, increased CAT activity appears to be linked to gene expression regulation, and decreased oxidative damage was identified in plants with higher CAT activity

This review underscores the gut microbiotas dual role as a biomarker and therapeutic target, advocating for microbiota-directed strategies in asthma prevention and precision medicine