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This occurs because GLP-1 receptors throughout the gastrointestinal tract influence gut motility and secretions when activated
In the series of 11 clinical trials (SUSTAIN programme) GLP-1 agonists demonstrated improved glycemic control in patients with diabetes (as measured by HbA1c) but also showed a consistent weight loss in trial participants
The researchers limited their analysis to participants who regularly interacted with the health care system the year before getting their injectable weight loss medication
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