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It's worth noting that this slowing of gastric emptying tends to diminish over time (tachyphylaxis) as the body adapts to treatment
Common complaints include: Increased tooth decay or cavities Some individuals notice new dental caries or worsening of existing decay, particularly along the gum line or between teeth Gum problems Gingivitis (gum inflammation), bleeding gums, receding gums, or periodontal disease may develop or worsen Tooth sensitivity Heightened sensitivity to hot, cold, or sweet foods and beverages Dry mouth (xerostomia) A persistent feeling of oral dryness, which can compromise the mouth's natural protective mechanisms Bad breath (halitosis) Persistent unpleasant breath odour that does not improve with routine oral hygiene Tooth discolouration or erosion Changes in tooth appearance, including yellowing, thinning of enamel, or visible wear patterns These symptoms may be indirectly related to the medication's mechanism of action and common adverse effects
Phase 2 trial data (NEJM, 2023) showed substantial MRI-PDFF-measured liver fat reductions at 8 mg and 12 mg weekly doses, with some participants falling below the 5% hepatic steatosis threshold
However, these diseases are difficult to treat given their complexity and the challenges of drug delivery to the brain [10, 11]
Can I treat cellulite naturally
