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Derived from a protein found naturally in human gastric juice, it is exceptionally stable

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The K29 chain elongation enzyme E3C, used in the second reaction step, also elongates K6, K11, K48, and K63 chains 31

[The relation of glutathione reductase and diaphorase activity of glutathione [PMID: 2679896] Laboratory literature summary: [The relation of glutathione reductase and diaphorase activity of glutathione reductase from Saccharomyces cerevisiae]