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The preclinical findings that there is no tolerance development toward the GLP-1R agonists tested and that the decline in drinking persists after treatment discontinuation suggest clinical applicability ( In conclusion, these preclinical and clinical studies point toward the possibility of using GLP-1R agonists to treat patients with addictions, an interaction that should be elucidated in future studies

And that's the number that may matter most.

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There was concern among potential plaintiffs at first that the court would set high standards for granting injunctions, but that doesnt seem to be happening

However, the decentralization of prescribing also introduces variability