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Our experiments have elucidated a coordinated mechanism underlying this phenomenon, characterized by the rapid induction of ISR and oxidative stress response (OSR), accompanied by increased GDF15 and FGF21, and a reduction in CoA levels resulting in metabolic inefficiency, therefore offering insights for potential intervention in metabolic diseases and body-weight control
Development of adenosine A2A receptor antagonists for the treatment of Parkinsons disease: a recent update and challenge
drug prices by up to 80% , reflecting the reality that Americans pay up to four times more than patients in OECD countries
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Da Silva T, Hafizi S, Andreazza AC, Kiang M, Bagby RM, Navas E, Laksono I, Truong P, Gerritsen C, Prce I, Sailasuta N, Mizrahi R
Possible role of PHD inhibitors as hypoxia-mimicking agents in the maintenance of neural stem cells' self-renewal properties
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