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In this context, besides their well described effect on solid tumors, reprogramming tumor resident macrophages using GPX4 inhibitors could be of potential interest in solid cancer and hematopoietic malignancies including AML

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Formulation matters

Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway