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Each of these mutant perilipin-1 proteins fails to bind ABHD5, resulting in unrestrained lipolysis, partial lipodystrophy, hypertriglyceridemia, and insulin resistance
In direct comparison trials for diabetes (SURPASS-2 compared tirzepatide to semaglutide 1 mg), tirzepatide showed superior blood sugar control and greater weight loss
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Nutritional adequacy should not be compromised despite reduced appetite
and Chiari, G
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