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Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
Researchers are also seeing improvements in blood pressure, inflammation, cholesterol, and liver fat, each of which is independently linked to heart risk
Moss CE, Marsh WJ, Parker HE, Ogunnowo-Bada E, Riches CH, Habib AM, et al
doi:10.1042/BJ20081386 67
These central effects translate into substantial weight loss - typically 5%-15% of body weight with current GLP-1 RAs - which directly ameliorates hepatic steatosis by reducing adipose tissue mass, reducing hepatic free fatty acid influx, and improving insulin sensitivity
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