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Ethics Approval This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors

However, the role of GLP-1R in the pathological process of OA is unclear

[23] [24] Suppressed glucagon secretion : These medications inhibit the release of glucagon from pancreatic alpha cells, which normally raises blood glucose by promoting hepatic glucose production

Active Ingredients and Mechanism of Action The sole active ingredient in this supplement is glutathione

Although the funnel plots indicated no publication bias, the variability in the findings calls for caution in interpreting the overall effectiveness of GLP-1RAs under these parameters