can tirzepatide cause skin sensitivity Does Allodynia? Side Effects and Safety Guide Bmi Doctors

Mode of action Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behaviour has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist

Curr Drug Targets 2006, 7: 1505-1512

And research to date hasnt shown whether the lean body mass lost while taking GLP-1s can be linked to any actual health issues

[7] Chronic exposure can eventually cause disease across multiple body systems, including peripheral neuropathy (numbness and tingling), enlargement of the liver and spleen, diabetes, heart disease, cognitive impairment, and damage to the portal vein (non-cirrhotic portal fibrosis and portal hypertension)

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