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The OASIS 4 trial, published in 2025, found that the 25-milligram oral dose of semaglutide produced an average weight loss of 13.6% over 68 weeks
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Liraglutide (Saxenda) was one of the earlier forms of longer-lasting GLP-1s and reduces HbA1c (average blood glucose) levels by around 1.3% on average and fasting plasma glucose by 2 mmol/L
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