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Graphical Abstract Keywords Insulin resistance, Lipid metabolism, Metabolic dysfunction-associated steatotic liver disease, MASLD, Oxidative stress, Silent information regulator 1, SIRT1, Therapeutic targeting Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic liver condition closely linked to metabolic abnormalities

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[53] Preliminary clinical data indicate improved reproductive function in PCOS, as seen by increased pregnancy rates in both natural and IVF cycles