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A: Results can vary, but many patients notice improvements in blood sugar levels within a few weeks of starting treatment
Sitagliptin attenuates myocardial apoptosis via activating LKB-1/AMPK/Akt pathway and suppressing the activity of GSK-3beta and p38alpha/MAPK in a rat model of diabetic cardiomyopathy
Biochem Biophys Res Commun , 2001;280(1):1328
And another refereed study released earlier this year by the Journal of Managed Care & Specialty Pharmacy revealed that 72% of individuals who started on GLP-1s for obesity were no longer taking them after one year
Likewise, studies in dementia have been mixed, but more definitive trials are underway (Mansur RB et al, J Affect Disord 2017;207:114120
