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411 G i2 also interacts with the engulfment and cell motility 1/dedicator of cytokinesis 1 (Elmo1/Dock180) complex, which acts as a RacGEF and activates Rac proteins, inducing actin polymerization and cell migration
For this reason, laboratories are encouraged to document their storage procedures in full and to record any anomalies, such as freezer malfunctions or suspected temperature fluctuations, that could affect outcomes
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Its primary function, however, lies in the oxidative stress response, where it assists in the detoxification of ROS as a critical cofactor for SodA (or MnSOD)
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