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Animal studies show robust activation of STING in heart, brain, and kidney after IR injury, and genetic or pharmacologic inhibition of STING reduces tissue damage and inflammation ( 2.1.2.4 Inflammasome-independent IL-33 and HMGB1 release Mitochondrial damage can also prompt stressed cells ( e.g

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A 2025 review of statins and vitamin D concluded that serum vitamin D is usually neutral or modestly higher on statin therapy, with potential synergy for endothelial and anti-inflammatory effects

Curr Hypertens Rep 2010