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A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007
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When to Contact Your Doctor About Zanamivir Side Effects Urgent Symptoms to Watch For Severe breathing difficulties or wheezing Swelling of the face, lips, tongue, or throat Severe rash or itching Persistent vomiting or dehydration Severe headache or confusion If you experience any of these symptoms, seek emergency care immediately
That balance is what makes this review useful
