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While the liver was previously thought to be the main target of metformins glucose-lowering effects, recent evidence suggests that other parts of the body, such as the gastrointestinal tract, also play a role in its overall clinical advantages
The physician who approves the original prescription remains accessible, though not necessarily in real time
G., Goula, A., Dimitriou, E
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Clinical trials show that nausea peaks between days 7-14 in most patients, with gastrointestinal effects appearing before appetite suppression becomes pronounced
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