Retatrutide is the developmental designation for an investigational compound owned by Eli Lilly and Company
Dose-dependent reductions in A1C and body weight at higher doses in people with type 2 diabetes have been demonstrated in the phase 2 evaluation of oral semaglutide, suggesting that oral semaglutide at higher doses may provide a more individualized treatment option in people with type 2 diabetes who need additional glycemic control and/or additional weight reduction, explained Sue Pedersen, MD, FRCPC, Specialist in Endocrinology and Metabolism at C-ENDO Diabetes & Endocrinology Clinic, Calgary, Canada
While the list price of $1,300 a month is floated a lot, thats not the amount drug companies charge much of the time
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If dosing is too high or continuous without breaks, the body will downregulate its own endogenous pathways and could become dependent or have blunted natural hormone production