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Compared to the GLP-1 receptor agonist semaglutide and placebo, tirzepatide demonstrated superior reductions in HbA1c (2.05%) and body weight (11.2kg) over 28 weeks

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527 Conclusions and perspective Primarily recognized for their role in diabetes mellitus treatment, GLP-1RAs have demonstrated significant benefits in cardiovascular health, skeletal muscle-related diseases, obesity management, and neurodegenerative conditions, among others