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Pigmented lesions on the mucosa: a wide range of diagnoses
Orlistat prevents dietary fat absorption by blocking lipase, an enzyme in the gut
Given that large, long-duration studies may be needed to demonstrate that a disease-modifying therapy is engaging the intended target and modifying disease progression, biomarkers can play an important role in phase 2 clinical trials to demonstrate proof of concept prior to initiating trials intended to demonstrate clinical benefit (Cummings, 2019
You also might not get the right amount or combination of ingredients to mimic true lipotropic injections, meaning supplements are less likely to be as effective in what you want them to do
It produces worse side effects
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