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Second, ferroptosis prevented by GPX4 might be one of the mechanisms that explain the relative immortal nature of cancer cells that contributed to poor prognosis in patients with GPX4-positive NSCLC in this study

To neutralize ROS, cells induce various antioxidant systems, including the activation of the protein machinery that produces glutathione [10], the most abundant antioxidant scavenger in all cells [11, 12]

Daily sun protection is essential for preventing hyperpigmentation and premature aging

As the body's most powerful endogenous antioxidant, glutathione plays critical roles in detoxification, immune function, and cellular protection

Of note, the NCCD suggests avoiding the term eryptosis due to the complexity and disputability of the life/death status of mature erythrocytes, notwithstanding the emphasis on its physiological and pathophysiological importance [4]