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(Neuropsychobiology 1992) documented a 59% improvement in sleep duration (+130 minutes) in chronic insomniac patients
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They act on different pathways
The primary efficacy endpoint assessed by the research team was the change from baseline in HbA1c levels following the 12 week experimental treatment period
Zhang, Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 247, (2021) 119145
Second, and this is just as important, the cold environment itself creates a hostile setting for any potential microbial contaminants that might have been introduced
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