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Moderate to Severe Deficiency: For moderate to severe deficiencies, the dosage may increase to 1,000 mcg several times a week initially, followed by a maintenance dose

Patients may experience more pronounced gastrointestinal symptoms during titration, which can influence their willingness to continue treatment

Employers took a range of approaches, with some using specialized vendors to provide case management and in other cases, organizing the requirement through the health plan

2023 Nov;176(11):JC129

In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks