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The computed energy barrier for Cu(II)-catalyzed methionine oxidation is 14.3 kcal/mol significantly lower than for Zn (19.6 kcal/mol) or Fe (16.9 kcal/mol), making copper the most efficient catalyst among common metal ions

In fact, reduced glutathione is up to 5,000 times more effective than other antioxidants, such as vitamin C, at quenching free radicals (Pizzorno, 2014)

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Bhalla, A., Bhargava, A., & Bhalla, K

This modification makes NAC a preferred choice for supplementation, as it can be absorbed more efficiently than L-cysteine when taken as a dietary supplement