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In conclusion, SAR425899 demonstrated strong interactions at the GLP1R, but no clear occupancy at the GCGR

Vegans and vegetarians may have lower baseline levels due to reduced dietary intake, though clinical deficiency in otherwise healthy individuals remains uncommon

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This heterogeneity may be attributed to differences in baseline HbA1c levels, obesity prevalence, trial duration, comparator treatments, dosing strategies, and outcome definitions

Effect of viscous fiber supplementation on obesity indicators in individuals consuming calorie-restricted diets: a systematic review and meta-analysis of randomized controlled trials