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Nonetheless, the therapeutic potential of glycine as a novel treatment for MASLD is supported by recent preclinical studies that demonstrated the ability of glycine-based supplements to reduce hepatic fat, inflammation, and fibrosis in rodents and non-human primates with MASLD 31,32
Their exact causes remain elusive, as does a definitive cure
However, results of recent early-stage clinical trials indicate GKAs lose their efficacy after several months of use
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