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Patients feel less hungry because these drugs slow the emptying of the stomach, so they feel full for longer. Ali said that while these drugs have been on the market for some time, theyve really gained in popularity in the past few years a factor thats led to shortages as manufacturers struggle to keep up with demand

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While earlier GHRPs activate multiple endocrine pathways causing spikes in cortisol, ACTH, prolactin, and appetite alongside GH ipamorelin produces a much cleaner GH-specific response