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Long R3 IGF-1 is modified to help increase its potency and stability while still exerting anabolic effects similar to IGF-1 Long stands for the additional 13 amino acids added to the N-terminus of the peptide molecule, while R3 describes the replacement of the 3rd amino acid in the native hormone with arginine

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Spectroscopy Fluorescence excitation spectra were collected using a LS55 fluorescence spectrophotometer (Perkin Elmer Life Sciences, Five hundred microliter protein solution was placed in a 1 ml quartz cuvette