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In comparison to ferroptosis-resistant cells, cells sensitive to ferroptosis accompanied by RAS mutation exhibit elevated TFR1 expression and reduced ferritin expression, indicating that higher iron import and lower iron storage may lead to ferroptosis (Yang and Stockwell, 2008)
However, FXR activation decreases both proglucagon mRNA levels and GLP-1 secretion in response to glucose [175, 176]
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