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Cytochrome c also binds to cardiolipin, and the Cytochrome c-cardiolipin conjugate opens up lipid pores in the membrane, resulting in the release of cytochrome c into the cytoplasm, thus facilitating its own escape and initiating an apoptosis cascade ( Table 1 provides a list of proteins that can form oligomers and interact with cardiolipin to induce pore formation and disease processes, with associated references

Additionally, we noted upregulation of p-Nrf2 and HO-1 protein expression upon inhibition of mitophagy (Fig

E., Eyre, R., Carvell-Miller, L., Leung, Y

Retinoids win on evidence quality