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In this context, when chitosan was used to modify the coreshell of NPs, the result was balanced mucus permeation, cellular uptake, and improved oral delivery of the drugs [56]

PLoS ONE 8 (4), e63197

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At the end point, cells were washed 3 times with saline and stained for 20 min at room temperature using a saline solution containing 0.2 mM l-glutamic acid -(4-methoxy--naphthylamide) (GMNA

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