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Supports research into collagen-related signaling, extracellular-matrix remodeling, and tissue repair [6] [7] [8]
Although the formation of TLS was shown to correlate with kidney damage, Havcr1 (the gene encoding Kim1) and Col1a1 mRNA expression was not attenuated by sulfasalazine treatment, despite the suppression of TLS (Figure 4F)
Further, analysis of the expression of bioenergetic pathways demonstrated pathways mainly activated in CTLax.3 and proliferating T cells ( Supplementary Figure 6C )
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