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So, why in 2023 were these products in such high demand that stock-outs occurred, and some pharmacies even resorted to unauthorized compounding

The 8 mg dose is a clinically acceptable maintenance target if the 12 mg dose produces persistent grade 2 or higher nausea, vomiting, or diarrhea after two failed escalation attempts [1, 8]

During the titration period and early weeks of therapy, a blander, lower-fat diet reduces GI disturbance

Reducing and combatting the formation of dysfunctional proteins and promoting the formation of healthy proteins [11]

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