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The SIRT1-weak/H3K18la-strong signature was found to be an independent prognostic factor in patients with GC

This visual assessment is supported by a statistical 2 -test, where the cost of the model ( v * for the optimal cost, see Methods ), given the optimal parameter values ( * , see Table S2), is below the threshold of rejection given by the 2 -test ( v * = 130.8 2

The price differential reflects bioavailability differences, as nasal formulations require higher peptide quantities to achieve comparable effects

Small, protein-rich meals spread throughout the day work best for managing GI side effects

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