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Animal studies at doses up to 50mg/kg daily for 90 days showed no organ toxicity
Whilst vitamin B12 toxicity is exceptionally rare due to its water-soluble nature, very high levelsparticularly from mega-dose supplements or frequent injectionshave been associated with certain adverse effects, most notably skin reactions
Researchers evaluated the peptide effects using two experimental models, ex vivo human hair follicles and cultured dermal papilla cells
A more sensitive assay lengthens the window without changing the pharmacokinetics at all
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